Anti-arthritic active fraction of Capparis spinosa L. fruits and its chemical constituents.

نویسندگان

  • Xiaolu Feng
  • Jincai Lu
  • Hailiang Xin
  • Lei Zhang
  • Yuliang Wang
  • Kexuan Tang
چکیده

The aim of this study was to ascertain the anti-arthritic active fraction of Capparis spinosa L. (Capparidaceae) fruits and its chemical constituents. The adjuvant arthritic rat model was developed to evaluate the anti-arthritic effects of different fractions of ethanol extraction from C. spinosa L. The fraction eluted by ethanol-water (50:50, v/v) had the most significant anti-arthritic activity. The chemical constituents of this fraction were therefore studied; seven known compounds were isolated and identified as: P-hydroxy benzoic acid; 5-(hydroxymethyl) furfural; bis(5-formylfurfuryl) ether; daucosterol; α-D-fructofuranosides methyl; uracil; and stachydrine.

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عنوان ژورنال:
  • Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan

دوره 131 3  شماره 

صفحات  -

تاریخ انتشار 2011